The Liver

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Oktober 2013



The Liver: Morphology, Biochemistry, Physiology, Volume I focuses on the advancement of knowledge on the liver under normal and pathological conditions, as revealed by morphological and physiological studies.
The selection first offers information on the embryonic liver and anatomy of the liver, including morphology and physiology of the embryonic liver, histology of the liver, surgical segments, and vascular gross anatomy of the liver. The text then elaborates on the structure of the liver sinusoids and the sinusoidal cells and the cyto- and histochemistry of the liver. Topics include protein reactions, nucleic acids, glycogen, lipids, heavy metals, and morphological aspects of lining cells.
The publication examines electron microscopy of the liver; acinar units and the pathophysiology of the liver; and dynamics of circulation in the liver. Discussions focus on oxygen transport and consumption in the liver; experimental alterations of the hepatic circulation; hexagonal pattern and the interdigitation of the afferent and efferent vascular trees; and simple liver acinus.
The selection is a dependable source of data for morphologists, biochemists, pharmacologists, and clinicians.


1;Front Cover;1 2;The Liver: Morphology, Biochemistry, Physiology;4 3;Copyright Page;5 4;Table of Contents;10 5;Contributors;6 6;Preface;8 7;Contents of Volume II;14 8;CHAPTER 1. THE EMBRYONIC LIVER;16 8.1;I. Morphology;16 8.2;II. Embryonic Liver Physiology;34 8.3;ACKNOWLEDGMENTS;47 8.4;REFERENCES;47 9;CHAPTER 2. ANATOMY OF THE LIVER;56 9.1;I. Histology of the Liver;56 9.2;IL Vascular Gross Anatomy of the Liver;69 9.3;III. Surgical Segments;71 9.4;REFERENCES;73 10;CHAPTER 3. THE STRUCTURE OF THE LIVER SINUSOIDS AND THE SINUSOIDAL CELLS;76 10.1;I. Historical and Theoretical Considerations;76 10.2;II. Morphological Aspects of Lining Cells;95 10.3;III. The Basement Membrane and the "Space of Disse";107 10.4;IV. Electron Microscopic Findings;118 10.5;REFERENCES;141 11;CHAPTER 4. CYTO- AND HISTOCHEMISTRY OF THE LIVER;152 11.1;I. Introduction;152 11.2;II. Nucleic Acids;154 11.3;III. Protein Reactions;157 11.4;IV. Glycogen;160 11.5;V. PAS-Positive Nonglycogenic Material;161 11.6;VI. Lipids;162 11.7;VII. Heavy Metals;163 11.8;VIII. Enzymatic Staining Reactions;165 11.9;IX. Discussion;195 11.10;REFERENCES;198 12;CHAPTER 5. ELECTRON MICROSCOPY OF THE LIVER;210 12.1;I. Introduction;210 12.2;II. The Hepatic Cell;211 12.3;III. The Biliary Pathways;250 12.4;IV. The Blood Sinusoids, the Kupffer Cells, and the Perisinusoidal Space;260 12.5;ACKNOWLEDGMENTS;266 12.6;REFERENCES;267 13;CHAPTER 6. ACINAR UNITS AND THE PATHOPHYSIOLOGY OF THE LIVER;280 13.1;I. Historical Note on the Microlobulation of the Liver;281 13.2;II. Simple Liver Acinus;284 13.3;III. The Complex Liver Acinus and the Acinar Agglomerate;294 13.4;IV. Hexagonal Pattern and the Interdigitation of the Afferent and Efferent Vascular Trees;299 13.5;V. Pathways of Hepatic Circulation;305 13.6;VI. Lines and Patterns Deriving from the Acinar Units for the Orientation of Hepatic Lesions;310 13.7;VII. Functional Anatomical Interpretation of Classical Notions in Pathology;316 13.8;VIII. Common Lesions in the Structural and Funct
ional Units of the Human Liver;320 13.9;IX. Summary;334 13.10;REFERENCES;337 14;CHAPTER 7. DYNAMICS OF THE CIRCULATION IN THE LIVER;346 14.1;I. Methodological Considerations;347 14.2;II. Results of Various Estimations of Hepatic Blood Flow;352 14.3;III. Oxygen Transport and Consumption in the Liver;365 14.4;IV. Hepatic Fractions of the Cardiac Output;372 14.5;V. Hepatic Circulation in Diseases of the Liver;374 14.6;VI. The Portal Pressure;376 14.7;VII. Experimental Alterations of the Hepatic Circulation;379 14.8;VIII. Concluding Remarks;386 14.9;REFERENCES;388 15;CHAPTER 8. THE CELL COMPONENTS OF THE LIVER;396 15.1;I. Introduction;396 15.2;II. Isolation of Cell Components;399 15.3;III. Morphology of Isolated Fractions;410 15.4;IV. Biochemistry of Isolated Cell Components;419 15.5;V. Conclusions;440 15.6;VI. Appendix: Isolated Liver Cells;443 15.7;ACKNOWLEDGMENTS;444 15.8;REFERENCES;444 16;CHAPTER 9. METABOLISM OF AMINO ACIDS AND PROTEINS;466 16.1;I. Introduction;467 16.2;II. General Picture of Amino Acid and Protein Metabolism;471 16.3;III. Free Amino Acid Levels: Concentration of Amino Acids by the Liver;487 16.4;IV. The Removal of Nitrogen as Ammonia from Amino Acids;491 16.5;V. Transamination of Amino Acids;497 16.6;VI. Other Mechanisms for the Removal of Nitrogen;502 16.7;VII. Urea Metabolism;505 16.8;VIII. Ammonia Metabolism;513 16.9;IX. Creatine-Creatinine Metabolism;517 17;CHAPTER 10. THE LIVER AND LIPID METABOLISM;566 17.1;I. Introduction: The General Role of the Liver;566 17.2;II. The Hepatic Lipids;568 17.3;III. Metabolism of the Fatty Acids;570 17.4;IV. The Synthesis and Degradation of Phospholipids;582 17.5;V. The Liver and the Circulating Lipids;589 17.6;VI. The Liver and the Metabolism of Cholesterol;598 17.7;REFERENCES;605 18;CHAPTER 11. THE LIVER AND CARBOHYDRATE METABOLISM;622 18.1;I. Introduction;623 18.2;II. Metabolism;624 18.3;III. Carbohydrate Metabolism and Hepatic Conjugation;637 18.4;IV. Energetics of Carbohydrate Metabolism;637 18.5;V. Mecha
nisms for the Regulation of Carbohydrate Metabolism;639 18.6;VI. Carbohydrate Metabolism as a Function of the Developmental State of the Organism;644 18.7;VII. Metabolic Diseases Due to Deficiencies in Enzymes of Carbohydrate Metabolism;645 18.8;REFERENCES;647 19;AUTHOR INDEX;652 20;SUBJECT INDEX;684

EAN: 9781483271750
Untertitel: Morphology, Biochemistry, Physiology. 200:Adobe eBook. Sprache: Englisch. Dateigröße in MByte: 103.
Verlag: Elsevier Science
Erscheinungsdatum: Oktober 2013
Seitenanzahl: 696 Seiten
Format: pdf eBook
Kopierschutz: Adobe DRM
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