Molecular Diagnostics in Dermatology and Dermatopathology

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März 2011



Molecular Diagnostics in Dermatology and Dermatopathology presents the basics of molecular biology and molecular diagnostic methods most commonly used in the clinical laboratory, with an emphasis on the concepts and testing most relevant to dermatological diseases. Topics include the integration of newer diagnostic and prognostic techniques with 'traditional' histologic approaches, and discussions of regulatory, ethical, legal, economic issues and 'newer' technologies. This important diagnostic tool outlines the clinically relevant uses (i.e.; diagnostic, staging and/or prognostic) applications of these techniques in the field of dermatology. Molecular studies that investigate the pathogenesis of skin diseases will be excluded, unless they also have a direct diagnostic utility. The book will be of interest to practicing pathologists, dermatology and pathology residents, dermatologists, and dermatopathologists.


    1.     Introduction to Molecular Diagnostic Testing in Dermatology and Dermatopathology
    2.      Principles of Molecular Biology
    3.      Technologies in the Molecular Diagnostics Laboratory
    4.      Cytogenetics of Primary Skin Tumors
    5.      Melanocytic Neoplasms I: Molecular Diagnosis
    6.      Melanocytic Neoplasms II: Molecular Staging
    7.      Non-Melanoma Skin Cancers and Hereditary Cancer Syndromes
    8.      Cutaneous Sarcomas and Soft Tissue Proliferations
    9.      Molecular Determination of Tissue Margins, Clonal Origin and Histogenesis of Skin Cancers
    10.  Mycosis Fungoides and Related Lesions
    11.  Cutaneous non-MF T-cell and NK-cell Lymphoproliferative Disorders
    12.  Cutaneous B-cell Lymphomas
    13.  Leukemia Cutis
    14.  Inflammatory Disorders of the Skin
    15.  Infectious Diseases of the Skin I: Dermatophytosis / Onychomycosis
    16.  Infectious Diseases of the Skin II: Non-Dermatophytic Infections
    17.  Wound Healing Disorders: Chronic Wounds and Keloids
    18.  Alopecias
    19.  Genodermatoses - Inherited Diseases of the Skin
    20.  Molecular Aspects of Skin Aging
    21.  Pharmacogenetics and Pharmacogenomics I: Linking Diagnostic Classification to Therapeutic Decisions
    22.  Pharmacogenetics and Pharmacogenomics II: Genetic Determinants of Drug Responses and Adverse Drug Reactions
    23.  Regulatory, Legal, Coding, Billing, Reimbursement, and Ethical Considerations for Molecular Diagnostic Testing in Dermatology and Dermatopathology



From the reviews:

'Molecular diagnostic testing has become established in so many areas of medicine in the past decade ' . Michael J. Murphy has enlisted a diversified group to experts to provide an introduction and update on many aspects of this rapidly changing field. ' This is not a book to read once and put aside. It contains a great deal of practical information that will be useful on an almost-daily basis when dealing with some of the classic difficult diagnoses in dermatopathology.' (Walter Burgdorf, Journal of Cutaneous Pathology, 2012)

EAN: 9781607611714
Untertitel: 2011. Auflage. 6 schwarz-weiße und 117 farbige Abbildungen, 63 schwarz-weiße Tabellen, Bibliographie. eBook. Sprache: Englisch. Dateigröße in MByte: 16.
Verlag: Humana Press
Erscheinungsdatum: März 2011
Seitenanzahl: xiii478
Format: pdf eBook
Kopierschutz: Adobe DRM
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