Molecular Biology of Human Cancers

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Februar 2005



Cancer research is now an interdisciplinary effort requiring a basic knowledge of commonly used terms, facts, issues, and concepts. This interdisciplinary book meets this need, providing an authoritative overview to the field. It presents many of the molecules and mechanisms generally important in human cancers and examines a broad, but exemplary, selection of cancers. In addition, cancer research has now reached a critical stage, in which the accumulated knowledge on molecular mechanisms is gradually translated into improved prevention, diagnosis, and treatment. This book summarizes the state, pitfalls, and potential of these efforts.


Part I.
1 An Introduction to Human Cancers.
2 Tumor Genetics.
3 DNA Damage and DNA Repair.
4 Oncogenes.
5 Tumor Suppressor Genes.
6 Cancer Pathways.
7 Apoptosis and Replicative Senescence in Cancer.
8 Cancer Epigenetics.
9 Invasion and metastasis.
Part II.
10 Leukemias and Lymphomas.
11 Wilms Tumor (nephroblastoma).
12 Cancers of the skin.
13 Colon Cancer.
14 Bladder Cancer.
15 Renal Cell Carcinoma.
16 Liver Cancer.
17 Stomach Cancer.
18 Breast Cancer.
19 Prostate Cancer. Part III.
20 Cancer Prevention.
22 Cancer Therapy.


From the reviews:
"Although Molecular Biology of Human Cancers is intended as a text for a graduate-level course, it is even more valuable for researchers like me, as a thoughtful encapsulation of the important areas of contemporary cancer research. ... the book is well designed as a text. The prose is clear, the numerous diagrams and tables are helpful ... . is unique in both coverage and perspective. Overall, I know of no other single source that provides a thoughtful view of more areas of molecular cancer research." (Joseph Locker, Angiogenesis, Vol. 7, 2004)
"This is a detailed and comprehensive review of the molecular aspects of cancer aetiology and development in man. It is aimed at advanced students and trainees in cancer-related disciplines and thus at a rather broad-spectrum audience. ... Overall, this is an interesting and informative book, which would be helpful to students wishing to have some in-depth knowledge of cancer genetics, and an overview of general concepts in this field ... ." (Shirley Hodgson, Human Genetics, Vol. 123, 2008)
EAN: 9781402031854
ISBN: 1402031858
Untertitel: An Advanced Student's Textbook. 202 illustrations. Sprache: Englisch.
Verlag: Springer-Verlag GmbH
Erscheinungsdatum: Februar 2005
Seitenanzahl: XIX
Format: gebunden
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