Coronary Disease in Women: Evidence-Based Diagnosis and Treatment

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Oktober 2003



It is now generally recognized that clinical trial investigators and research scientists at the molecular, genetic, and cellular levels need to perform more detailed gender-based research in order to understand how sex-based differences impact women's health, illness, and health care. In Coronary Disease in Women: Evidence-Based Diagnosis and Treatment, leading authorities and clinical experts review the data concerning coronary disease in women and provide a clinical management approach to the care of women with known or suspected coronary artery disease. Whereas earlier books have focused on gender-based differences in the epidemiology of coronary disease, or on gender bias in its treatment, the present work focuses on the daily, evidence-based clinical management of coronary disease in women. Working from the recommendations of the landmark Institute of Medicine's report, Exploring the Biological Contributions to Human Health: Does Sex Matter?, the authors apply the latest epidemiological findings and diagnostic tools to the evaluation of stable chest pain and acute ischemic syndromes in women. They also detail the therapeutic effectiveness of various treatments in women, such as coronary revascularization, electrophysiology, exercise training and cardiac rehabilitation, and menopausal hormone therapy. Additional chapters examine the effects of gender bias in diagnosis and treatment, the role of gynecologists as primary care physicians for women, health technology assessment in an era of managed care, and the problems of analyzing cost-effectiveness in the diagnosis and treatment of coronary artery disease in women. Authoritative and timely, Coronary Disease in Women: Evidence-Based Diagnosis and Treatment provides primary care physicians, cardiologists, family practitioners, gynecologists, and internists with an up-to-date guide to the optimal management of coronary disease in women today.


Part I. Introduction

The Institute of Medicine Report, Women's Cardiovascular Health, and Evidence-Based Medicine
Nanette K. Wenger

Evidence-Based Medicine in the Assessment of Women at Risk for Cardiovascular Disease
Leslee J. Shaw

Part II. Screening and Diagnosis of Coronary Disease in Women

A. Cardiovascular Epidemiology in Women

Population-Based Sex Differences in Disease Incidence and Prevalence
Brandi J. Witt and Véronique L. Roger

Risk Detection and Primary Prevention in Women
Lori Mosca and Leslee J. Shaw

Early Detection of Coronary Artery Disease in Women: Role of Coronary Artery Calcium Scanning With EBT
John A. Rumberger

Heart Failure in Women: Epidemiology, Gender Differences in Pathophysiology, and Implications for Therapy
Daniel P. Morin, Marvin A. Konstam, Michael E. Mendelsohn, and James E. Udelson

Diastolic Dysfunction in Women
Mary Norine Walsh and Mariell Jessup

Functional Capacity and Activities of Daily Living in Women
Claire E. Pothier Snader and Michael S. Lauer

Special Considerations for Minority Women
Jennifer H. Mieres and Elizabeth Ofili

B. Varying Symptom Presentation in Women

Clinical Risk Assessment in Women: Chest Discomfort: Report from the WISE Study
B. Delia Johnson, Sheryl F. Kelsey, and C. Noel Bairey Merz

Quality-of-Life Issues for Women With Coronary Disease
John Spertus and Darcy Green-Conaway

C. Choosing the Best Diagnostic Test for Women

Should All Women With Suspected Coronary Disease Undergo Stress Cardiac Imaging?
Anthony P. Morise

State-of-the-Art Diagnostic Testing in Women: A Research Update
Leslee J. Shaw, B. Delia Johnson, Sharon Mulvagh, Jennifer H. Mieres, Rita F. Redberg, and C. Noel Bairey Merz

Part III. Management of Coronary Disease inWomen

A. Evaluation of Stable Chest Pain Syndromes in Women

Treatment Strategies for Women With Stable Angina, Paul R. Casperson, Leslee J. Shaw, and Robert A. O'Rourke

Improving the Diagnosis and Management of Women With Coronary Disease in Primary Care Settings
Kimberly J. Rask

B. Evaluation of Acute Ischemic Syndromes in Women

Evaluation of Acute Chest Pain in Women
Andra L. Blomkalns, W. Brian Gibler, and L. Kristin Newby

Acute Ischemic Syndromes: Differences in Presentation and Treatment in Women
Jane A. Leopold and Alice K. Jacobs

C. Variations in Therapeutic Effectiveness in Women

Effectiveness of Coronary Revascularization: Gender and Racial Differences
Christi Deaton, Cherie L. Kunik, and Eric Peterson

Electrophysiology: Treatment Considerations in Women
Michael S. Bailey and Anne B. Curtis

Exercise Training and Cardiac Rehabilitation for Women
Elisa Yuen Man Chiu, Maria Vivina T. Regis, and Erika Sivarajan Froelicher

Menopausal Hormone Therapy: Is There Evidence for Cardiac Protection?
Nanette K. Wenger

Part IV. Economics and Policy Issues in Health Care Related to Women

Gender Bias: Is It Real and How Does It Affect Diagnosis, Management, and Outcome?
Thomas H. Marwick and Jonathan Chan

The Role of Women's Health Centers in Improving Access and Process of Care
Susan Kendig and D. Douglas Miller

Obstetrician/Gynecologists, Primary Care, and Cardiovascular Disease
William W. Hurd, Sheela Barhan, and Robert E. Rogers

Health Technology Assessment in the Era of Managed Care: Issues in Women's Health Care
Laura Sampietro-Colom, Shawna Jackson, Erin Williams, and Frank J. Papatheofanis

Issues in the Analysis of Cost-Effectiveness in the Diagnosis and Treatment of Coronary Artery Disease in Women
Adam Atherly and Steven


"...contemporary and up-to-date review of women and coronary artery disease." - Texas Heart Institute Journal
"The book provides a good overview of the various ways in which women with known or suspected CAD differ from men, whether from the epidemiologic, clinical, or management perspective. This text will provide a wake-up call for clinicians who are not sufficiently sensitive to the potentially pernicious and corrosive effects of gender bias in the management of CAD in women." - Annals of Internal Medicine
"There is much to be learned from this book..." -New England Journal of Medicine
"Comprehensive and highly practical...offers both basic and clinical scientists an up-to-date collection of cutting edge protocols for solving he widest variety of novel flow cytometry problems." - Clin Lab
"All methods are described in detail, and this book has the potential to become the geneticist's and biochemist's 'cook book' to study recombination in eukaryotes. It provides both experts and novices that want to move into the field of recombination with an accessible provides trouble-shooting guides and the principles behind techniques as well as describing the basics of recombination." - ChemBioChem
"...excellent book on all aspects of coronary artery disease (CAD) in women." - Doody's Health Sciences Book Review Journal
EAN: 9780896039582
ISBN: 0896039587
Untertitel: 'Contemporary Cardiology (Hardc'. 2004. Auflage. Sprache: Englisch.
Erscheinungsdatum: Oktober 2003
Seitenanzahl: 431 Seiten
Format: gebunden
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