Programmed Cell Death, Volume I: Cellular and Molecular Mechanisms

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Mai 2001



Apoptosis, or programmed cell death, is an adaptive form of cell death that plays a critical role in turnover of mitotic cells and various tissues in the adult, including epithelial cells, fibroblasts and various endocrine cells. This book details the molecular, biochemical and cellular mechanisms of apoptosis.


Mechanisms underlying the hallmark features of the execution-phase of apoptosis (J. Mills); death domain signaling and its role in the central nervous system (A.J. Bruce-Keller); diversity of caspase involvement in neuronal cell death (C.M. Troy); mitochondrial control of apoptosis (B. Mignotte, J.-L. Vayssiere); proliferative mitochondrial dysfunction and apoptosis (M. Mancini, S. Camilleri-Broet, B.O. Anderson, D.M. Hockenbery); the Bcl-2 family of proteins and their actions within the molecular machinery of cell death (Qing Guo, Sic L. Chan, I. Kruman); the role of Jun-Kinases in apoptosis (S.P. Tammariello, G.E. Landreth, S. Estus); apoptosis by Par-4 protein (V.M. Rangnekar); cytoskeletal involvement in apoptosis (R.K. Srivastava, D.L. Longo); anti-apoptotic role of the transcription factor NF-kB (M.P. Mattson); inhibitor of apoptosis proteins (IAPS) (Q.L. Deveraux, J.C. Reed); excitotoxins, nitric oxide and programmed neuronal death (M. Leist, P. Nicotera).


S.I.S. Rattan ...provides an extensive background to cellular and molecular basis of apotosis. Biogerontology
EAN: 9780444504937
ISBN: 0444504931
Untertitel: New. Sprache: Englisch.
Erscheinungsdatum: Mai 2001
Seitenanzahl: 368 Seiten
Format: gebunden
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