Cancer Cytogenetics

€ 126,99
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März 2003



Cytogenetic studies of malignancy have become an essential tool in the clinical management of cancer patients, but they are not uniformly utilized, even in well-developed countries. In Cancer Cytogenetics: Methods and Protocols, experienced cytogeneticists describe in step-by-step detail the key cytogenetic and FISH techniques used by modern clinical laboratories in the genetic analysis of human malignancies, as well as explain how best to interpret the results. The book's practical advice and methods are suitable for use at every level of expertise, including fully established laboratories, but with a sympathetic bias toward anyone considering setting up a new cytogenetics service. Here the reader will find not only elementary tutorials on the fundamentals of human karyotypes and chromosome analysis, but also detailed discussions on how laboratories may optimally upgrade their repertoire of available capabilities to include such newer complementary techniques as CGH, FISH, and M-FISH. Each protocol contains many novel ideas and time-saving techniques, expert commentary, tricks of the trade, alternative approaches, and suggestions that will help yield the results that clinicians want. Eminently practical for every stage of diagnostic service, Cancer Cytogenetics: Methods and Protocols offers hospital and other pathology laboratories a user-friendly collection of both standard and advanced techniques, all carefully designed to improve the diagnosis and clinical management of cancer patients today.


John Swansbury

Cytogenetic Studies in Hematologic Malignancies: An Overview
John Swansbury

The Myeloid Disorders: Background
John Swansbury

Cytogenetic Techniques for Myeloid Disorders
John Swansbury

Acute Lymphoblastic Leukemia: Background
John Swansbury

Conventional Cytogenetic Techniques in the Diagnosis of Childhood Acute Lymphoblastic Leukemia
Susana C. Raimondi and Susan Mathew

Chromosome Preparations from Bone Marrow in Acute Lymphoblastic Leukemia: Cytogenetic Techniques
Ann Watmore

Lymphoid Disorders Other than Common Acute Lymphoblastic Leukemia: Background
John Swansbury

Other Lymphoid Malignancies: Cytogenetic Techniques
John Swansbury

Cytogenetic and Genetic Studies in Solid Tumors: Background
John Swansbury

Human Solid Tumors: Cytogenetic Techniques
Pietro Polito, Paola Dal Cin, Maria Debiec-Rychter, and Anne Hagemeijer

Analysis and Interpretation of Cytogenetic Findings in Malignancies
John Swansbury

Cytogenetic Studies Using FISH: Background
Toon Min and John Swansbury

FISH Techniques
Toon Min

FISH, CGH, and SKY in the Diagnosis of Childhood Acute Lymphoblastic Leukemia
Susan Mathew and Susana C. Raimondi

Solving Problems in Multiplex FISH
Jon C. Strefford

Some Difficult Choices in Cytogenetics
John Swansbury

Introduction to the Analysis of the Human G-Banded Karyotype
John Swansbury


About the Authors


"Eminently practical for every stage of diagnostic service, this book offers laboratories a user-friendly collection of standard and advanced techniques, carefully designed to improve diagnosis and clinical management of cancer patients." - Clinical Laboratory International
" immensely useful book for anyone working in the field of cytogenetics. The author has filled this volume with the sort of detail that enables ready translation of methods into practice and provides clear explanations of individual steps within procedures..." - Cancer Forum
EAN: 9781588290809
ISBN: 1588290808
Untertitel: 'Methods in Molecular Biology'. Sprache: Englisch.
Erscheinungsdatum: März 2003
Seitenanzahl: 283 Seiten
Format: gebunden
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