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Advances in Medicinal Chemistry

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April 1999

Beschreibung

Beschreibung

Comprises of six chapters on a range of topics in medicinal chemistry, including molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment, structure-activity correlation, and lead optimization.

Inhaltsverzeichnis

Preface. Novel peptide mimetic building blocks and strategies for efficient lead finding. Recent advances in the medicinal chemistry of taxoid anticancer agents. Synthesis and structure-activity relationships of peroxidic antimalarials based on artemisinin. Design of compound libraries for detecting and pursuing novel small molecule leads. A theoretical model of the human thrombin receptor (PAR-1), the first known protease-activated G-protein-coupled receptor. Farnesyl transferase inhibitors: design of a new class of cancer chemotherapeutic agents.
EAN: 9780762300648
ISBN: 0762300647
Untertitel: Sprache: Englisch.
Verlag: ELSEVIER SCIENCE & TECHNOLOGY
Erscheinungsdatum: April 1999
Seitenanzahl: 321 Seiten
Format: gebunden
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